How Long Does Kratom Stay in Your System?

Kratom, a tropical tree native to Southeast Asia, has gained popularity in the United States and other parts of the world for its opioid-like effects and stimulant properties. While it has been used traditionally and unofficially to treat pain, enhance energy, and manage opioid withdrawal, concerns about kratom abuse, kratom dependence, and its detection in drug tests have increased significantly in recent years.

One of the most commonly asked questions by users and healthcare providers alike is: How long does kratom stay in your system? The answer isn’t simple. It depends on several physiological and pharmacological variables.

Understanding Kratom: Alkaloids and Effects

Kratom, or Mitragyna speciosa, contains two primary kratom alkaloids—mitragynine and 7-hydroxymitragynine—that interact with the brain’s opioid receptors. These alkaloids are responsible for the plant’s sedative effects at high doses and stimulant effects at low doses.

Because kratom interacts with the same receptors as opioids, its use can lead to physical dependence, kratom withdrawal, and, in some cases, kratom addiction, especially with chronic use or high doses.

Kratom’s Half-Life and Metabolization Process

The half-life of a substance is the time it takes for half of it to be eliminated from the body. Research suggests that mitragynine, the most abundant kratom alkaloid, has a half-life of about 24 hours, though it can range from 7 to 40 hours depending on the individual.[1]

Since it takes approximately 5 half-lives to eliminate a drug, kratom may stay in a person’s system for up to 5 to 10 days, depending on dosage and individual factors.

Factors Affecting How Long Kratom Stays in Your System

Several variables influence how long kratom stays in your system:

Dosage

High doses (10 grams or more) remain in the system longer than small doses (2–5 grams).
Additionally, chronic use can lead to accumulation in the body, extending the clearance period.

Frequency of Use

Occasional users may metabolize kratom more quickly than those with habitual kratom use.

Body Weight and Body Fat

Kratom is fat-soluble, meaning it can be stored in body fat and released slowly over time.

Metabolic Rate

A person’s metabolic rate and liver function are crucial. Faster metabolism leads to faster elimination.

Age

Older individuals typically metabolize substances more slowly than younger adults.

Other Substances

Taking other drugs or supplements that affect liver enzymes can alter how quickly kratom is metabolized.

How Is Kratom Detected in Drug Tests?

Unlike substances such as cocaine or opioids, kratom is rarely tested for in most standard drug tests. However, specialized tests can detect kratom and its metabolites in various biological samples.

Urine Tests

Urine testing is the most common method for detecting kratom. Mitragynine can typically be detected in urine for up to 7–9 days after last use. This varies depending on kratom dose and frequency of use.

Blood Tests

Blood tests may detect kratom for 1 to 3 days. These are less commonly used due to the shorter detection window.

Hair Tests

While uncommon, hair follicle testing could detect kratom for up to 90 days, similar to other substances. However, this is rarely employed due to analytical challenges and limited standardization.

Saliva Tests

Not a reliable method for kratom detection; typically not used.

Panel Drug Tests

Kratom is not included in most standard panel drug tests (such as the 5-panel or 10-panel tests). However, certain extended panels may include mitragynine if kratom abuse is suspected.

Why Is Kratom Not Widely Tested?

One reason kratom is rarely tested in workplaces or legal settings is due to limited research, analytical challenges, and a lack of regulation.

Although the Drug Enforcement Administration (DEA) attempted to designate kratom as a Schedule I substance in 2016, public and scientific backlash led to a reversal. As of now, kratom is not federally scheduled, though some states and municipalities have banned or regulated it.

Despite this, the DEA continues to monitor kratom as a “drug of concern,” citing its potential for substance abuse and addiction.[2]

Kratom Withdrawal and Dependence

Like opioids, chronic kratom use can lead to kratom dependence and withdrawal syndrome. Common kratom withdrawal symptoms include:[3]

• Muscle aches
• Insomnia
• Irritability
• Nausea
• Diarrhea
• Anxiety
• Runny nose

These symptoms can begin within 12 to 48 hours after cessation and last up to a week, depending on the person’s system, dosage, and usage history.

This makes kratom addictive for some users, especially those using it to self-treat chronic pain or as a replacement for opioid withdrawal.

Health Risks and Overdose Potential

Although many view kratom as a natural alternative to opioids, it still carries health risks:

• Liver damage in rare cases
• Respiratory depression at high doses or when combined with other substances
• Risk of unintentional drug overdose deaths, especially when mixed with depressants like alcohol or benzodiazepines

According to the CDC, from July 2016 to December 2017, kratom was detected in 152 of 27,338 unintentional drug overdose deaths. In 91 of those cases, kratom was the only substance found.[4]

Addiction Treatment and Support

For individuals experiencing kratom addiction or struggling with withdrawal symptoms, addiction treatment options are available. These may include:

• Medical detox
• Behavioral therapy
• Support groups
• Individualized care plans from healthcare professionals

Facilities offering treatment for substance abuse increasingly include kratom in their assessments due to its rising popularity and potential for misuse.

Get Connected to Kratom Addiction Treatment

Ultimately, how long kratom stays in your system depends on numerous individual and pharmacological factors. While the average detection window for urine is around a week, users with high doses, chronic use, or slower metabolism may retain kratom metabolites longer.

As kratom continues to be used for pain relief, opioid withdrawal, or recreation, awareness of its potential for dependence, withdrawal, and the risk of kratom abuse is crucial.

If you or a loved one suffers from kratom addiction, it’s time to seek professional help. At Flourishing Foundations Recovery, we can help you achieve long-lasting recovery. Contact us today to learn more about our kratom addiction treatment program.

Frequently Asked Questions (FAQ)

1. Can kratom cause a false positive on a drug test?

No, kratom does not typically cause a false positive for opioids or other common drugs in standard drug tests. The main alkaloids in kratom, mitragynine and 7-hydroxymitragynine, are chemically distinct from most scheduled drugs. However, specialized tests designed to detect kratom specifically can identify its presence if requested.

2. Is it safe to mix kratom with other medications or substances?

Mixing kratom with prescription medications, alcohol, or other drugs can be dangerous and may increase the risk of serious side effects such as respiratory depression, liver stress, or central nervous system suppression. There is limited clinical research on drug interactions with kratom, so users should exercise caution and consult a healthcare provider before combining kratom with other substances.

3. Does kratom show up on military or court-ordered drug tests?

Although most standard drug panels don’t test for kratom, some military or court-supervised programs may use expanded drug testing panels that include mitragynine detection. Because kratom use can be prohibited under certain conditions (e.g., probation, military regulations), individuals in those settings should confirm testing policies with relevant authorities.

4. How long should I stop using kratom before a drug test?

To reduce the risk of detection, abstaining for at least one to two weeks is generally recommended. However, this depends on dose, frequency, body composition, and metabolism. Frequent or high-dose users may require more time for complete elimination.

5. Are over-the-counter kratom products regulated for purity?

No, kratom products sold in stores or online are not federally regulated in the U.S. for quality, potency, or purity. This means they may contain inconsistent levels of active alkaloids or be adulterated with other substances. Look for products that are lab-tested and carry certifications from independent third parties if you choose to use kratom.

6. Can kratom use affect liver enzymes or blood work results?

Yes, there are case reports indicating kratom may elevate liver enzymes, which can show up on routine blood panels. These elevations may suggest liver stress or damage, especially in individuals with pre-existing liver conditions or those using large doses. If you’re undergoing medical testing, inform your healthcare provider of any kratom use.

References:

1. The National Library of Medicine (NLM): Kratom
2. The Drug Enforcement Administration (DEA): Kratom
3. Science Direct: Kratom withdrawal: Discussions and conclusions of a scientific expert forum
4. The Centers for Disease Control and Prevention (CDC): Notes from the Field: Unintentional Drug Overdose Deaths with Kratom Detected — 27 States, July 2016–December 2017